※This product is for 2 persons

About Gene-Checker (Infertility)

Inspection Overview

Infertility is thought to affect approximately one in six couples worldwide, with male infertility accounting for about 35% and female infertility about 45% (the remaining cases are a combination of both).
Further to the breakdown, biochemical and instrumental tests such as hormonal tests, ultrasound and semen tests can identify up to 65% of infertility cases, and 10-15% of all men and women have genetic changes associated with infertility.
Gene-Checker (Infertility) is a genetic test for infertility that screens for genetic mutations in individuals who have difficulty conceiving.Gene-Checker (Infertility) provides an accurate prognostic assessment by identifying genetic mutations associated with infertility and sex chromosome disorders, and helps identify treatment options. and help to identify treatment options.

  
Eligible Persons

・Women who have had a previous hyperemesis gravidarum
・Women with irregular or no menstruation
・Suspected sexual development disorder
・Women who plan to undergo assisted reproductive technology (ART) treatment
・Candidates for sperm or egg donation
・Those with a family history of infertility
・Those who have had two or more miscarriages
・Those with a family history of neonatal alloimmune thrombocytopenia (NAIT)

Notes

The assay does not identify all mutations associated with the disease being tested. Although the assay is very accurate, false positive or false negative results may occur. This is due to technical and/or biological limitations, including, for example, sample mislabelling, inaccurate reporting of clinical medical information, rare technical errors and other events. Genetic changes not detected by Gene-Checker (infertility) may also be associated with disease. Although genetic testing is an important part of the diagnostic process, it does not always provide definitive answers. In some cases, a genetic variant may be present but not identified by testing. This is due to the limitations of current medical knowledge and testing techniques. Clinical correlation with other clinical data and tests is recommended. Results should always be considered in the context of other clinical criteria. The referring physician should be responsible for providing pre- and post-test counselling and advice on the need for additional genetic testing, and other diagnostic tests may still be required.

Testable Diseases and Corresponding Genes

Female Infertility Panel

 Thrombosis and Neonatal Alloimmune Thrombocytopenia (NAIT) Panel